Histone H3R2me1 Polyclonal Antibody


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Cat.No.:  EAb-0590
Product Name:  Histone H3R2me1 Polyclonal Antibody
Product Overview:  Anti-Histone H3 [Monomethyl Arg2] (RABBIT) Antibody
Antibody Type:  Polyclonal
Immunogen:  Prepared from whole rabbit serum produced by repeated immunizations with a synthetic monomethylated peptide surrounding Arginine 2 of human Histone H3.2.
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purified from monospecific antiserum by immunoaffinity chromatography.
Appearance:  Liquid
Formulation:  0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Applications:  Western Blot
Recommended Dilutions/Conditions:  Western Blot: 1:500
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Cross Reactivity:  Human, mouse, C. elegans, rat, chicken, Xenopus, Drosophila, plant
Shipping:  Dry Ice
Storage:  -20°C
Storage Buffer:  0.01% (w/v) Sodium Azide
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  UniprotKB - Q71DI3; NCBI - NP_001005464; GeneID - 126961
Alternative Name:  rabbit anti-Histone H3 monomethyl Arg2 antibody, H3.3B, H3 histone, family 3A, H3.3AH3F3H3F3B, histone H3.3, MGC87783, MGC87782, H3R2me1
Scientific Background:  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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