| Cat.No.: | EAb-0602 |
| Product Name: | Histone H2A.Zac pan Polyclonal Antibody |
| Product Overview: | Anti-Histone H2 A.Zac pan (RABBIT) Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Produced in rabbits by repeated immunizations with a synthetic peptide from histone H2A.Z acetylated at lysines 5, 7 and 11. |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Purified by affinity purification. |
| Appearance: | Liquid |
| Formulation: | 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2 |
| Applications: | Chromatin Immunoprecipitation, Dot Blots, ELISA and Immunofluorescence |
| Recommended Dilutions/Conditions: |
ELISA: 1:200; ChIP: 1 μg per IP; Dot Blot: 1:20,000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Cross Reactivity: | Human |
| Shipping: | Dry Ice |
| Storage: | -20°C |
| Storage Buffer: | 0.05% (w/v) Sodium Azide and 0.05% ProClin 300 |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | UniProtKB - P0C0S5; GeneID - 3015; NCBI - NP_002097 |
| Alternative Name: | Histone H2A.Z, H2A/z |
| Scientific Background: | Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0020 | Recombinant Nucleosome, H2AR3me1 dNuc | Inquiry |
| NUC-0021 | Recombinant Nucleosome, H2AR3me2a dNuc | Inquiry |
| NUC-0075 | Recombinant Nucleosome, H2AK119ub dNuc | Inquiry |
| NUC-0076 | Recombinant Nucleosome, H2BK120ub dNuc | Inquiry |
| NUC-0082 | Recombinant Nucleosome, H2AXS139phos dNuc | Inquiry |
| Related Gene / Proteins | |||
| H2AK11 | H2AK119 | H2AK12 | H2AK13 |
| H2AK15 | H2AK16 | H2AK4 | H2AK5 |
| H2AK7 | H2AK8 | H2AK9 | H2AP26 |
| H2AQ104 | H2AR29 | H2AR3 | H2AS1 |
| H2AS129 | H2AS139 | H2AS2 | H2AT120 More > |
| H2AT121 | H2AT142 | H2AY142 | H2BK108 |
| H2BK11 | H2BK116 | H2BK12 | H2BK120 |
| H2BK126 | H2BK15 | H2BK16 | H2BK20 |
| H2BK23 | H2BK43 | H2BK46 | H2BK5 |
| H2BR79 | H2BS112 | H2BS14 | H2BS32 |
| H2BT129 | |||
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