Histone H3K37me1 Polyclonal Antibody


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Cat.No.:  EAb-0734
Product Name:  Histone H3K37me1 Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications:  ELISA, WB
Recommended Dilutions/Conditions:  WB: 1:500-1:2000, ELISA: 1:20000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse, Rat
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1;
Scientific Background:  Chromatin is the arrangement of DNA and proteins in which chromosomes are formed. Correspondingly, chromatin is formed from nucleosomes, which are comprised of a set of four histone proteins (H2A, H2B, H3, H4) wrapped with DNA. Chromatin is a very dynamic structure in which numerous post-translational modifications work together to activate or repress the availability of DNA to be copied, transcribed, or repaired. These marks decide which DNA will be open and commonly active (euchromatin) or tightly wound to prevent access and activation (heterochromatin). Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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