Histone H3K36me3 Polyclonal Antibody


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Cat.No.:  EAb-0736
Product Name:  Histone H3K36me3 Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Applications:  ChIP, ChIPseq, IF, IHC, IP, WB
Recommended Dilutions/Conditions:  WB, IHC, IF, IP, ChIP, ChIPseq; Recommended dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 ChIP 1:20 - 1:100 CHIPseq 1:20 - 1:100
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  BroadRange, Human, Mouse, Rat
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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