| Cat.No.: | EAb-0759 |
| Product Name: | Histone H2BK5me1 (H2BK5 Monomethyl) Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Appearance: | Liquid |
| Formulation: | PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Applications: | WB |
| Recommended Dilutions/Conditions: |
WB: 1:500-1:1000, ELISA: 1:20000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | HIST1H2BA; TSH2B; Histone H2B type 1-A; Histone H2B, testis; Testis-specific histone H2B; HIST1H2BB; H2BFF; Histone H2B type 1-B; Histone H2B.1; Histone H2B.f; H2B/f; HIST1H2BC; H2BFL; HIST1H2BE; H2BFH; HIST1H2BF; H2BFG; HIST1H2BG; H2BFA; HIST1H2BI; H2BFK |
| Scientific Background: | Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells (By similarity). Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones (By similarity). Core component of nucleosome (By similarity). Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template (By similarity). Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability (By similarity). DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Also found in fat cells, its function and the presence of post-translational modifications specific to such cells are still unclear. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0020 | Recombinant Nucleosome, H2AR3me1 dNuc | Inquiry |
| NUC-0021 | Recombinant Nucleosome, H2AR3me2a dNuc | Inquiry |
| NUC-0075 | Recombinant Nucleosome, H2AK119ub dNuc | Inquiry |
| NUC-0076 | Recombinant Nucleosome, H2BK120ub dNuc | Inquiry |
| NUC-0082 | Recombinant Nucleosome, H2AXS139phos dNuc | Inquiry |
| Related Gene / Proteins | |||
| H2AK11 | H2AK119 | H2AK12 | H2AK13 |
| H2AK15 | H2AK16 | H2AK4 | H2AK5 |
| H2AK7 | H2AK8 | H2AK9 | H2AP26 |
| H2AQ104 | H2AR29 | H2AR3 | H2AS1 |
| H2AS129 | H2AS139 | H2AS2 | H2AT120 More > |
| H2AT121 | H2AT142 | H2AY142 | H2BK108 |
| H2BK11 | H2BK116 | H2BK12 | H2BK120 |
| H2BK126 | H2BK15 | H2BK16 | H2BK20 |
| H2BK23 | H2BK43 | H2BK46 | H2BK5 |
| H2BR79 | H2BS112 | H2BS14 | H2BS32 |
| H2BT129 | |||
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
