SPDL1 Polyclonal Antibody, FITC Conjugated


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Cat.No.:  EAb-0786
Product Name:  SPDL1 Polyclonal Antibody, FITC Conjugated
Antibody Type:  Polyclonal
Conjugate:  FITC
Host:  Rabbit
Isotype:  IgG
Purification:  Protein G Purified
Appearance:  Liquid
Formulation:  0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
Applications:  ELISA
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  Protein Spindly, Arsenite-related gene 1 protein, Coiled-coil domain-containing protein 99, SPDL1
Scientific Background:  Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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