SMARCE1 Polyclonal Antibody


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Cat.No.:  EAb-0793
Product Name:  SMARCE1 Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Applications:  IF, IHC, WB
Recommended Dilutions/Conditions:  WB, IHC, IF; Recommended dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  BAF57
Scientific Background:  The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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