Phospho Histone H3 (Ser10) Monoclonal Antibody


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Cat.No.:  EAb-1098
Product Name:  Phospho Histone H3 (Ser10) Monoclonal Antibody
Antibody Type:  Monoclonal
Conjugate:  Unconjugated
Host:  Mouse
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  PBS (pH 7.5), 150 mM NaCl, 30% glycerol
Applications:  ChIP, ELISA, IF, IHC, IP, WB
Recommended Dilutions/Conditions:  WB: 1:1000-1:2000, IF: 1:100-1:500, IHC: 1:100-1:500, ELISA: 1:1000-1:2000, IP: 2 μg/106 cells
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Broad Range, Human, Mouse, Rat
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  H3ser10P antibody
Scientific Background:  Histone H3– along with H2A, H2B, and H4– is involved in the structure of chromatin in eukaryotic cells. Histone H3 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occur on the N-terminal tail domains of histone H3, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H3 is primarily phosphorylated at serine 10, serine 28, threonine 3, and theonine11.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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