Phospho Histone H3.3 (Ser32) Polyclonal Antibody


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Cat.No.:  EAb-1124
Product Name:  Phospho Histone H3.3 (Ser32) Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Applications:  WB
Recommended Dilutions/Conditions:  WB; Recommended dilution: WB 1:500 - 1:2000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse, Rat
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  H3F3, H3.3A
Scientific Background:  Histones are proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. Nucleosomes consist of about 146-147 bp of DNA wrapped around an octamer of histone proteins (histone 2A, histone 2B, histone 3, and histone 4). The N-terminal tails of histones protrude from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. The interaction of linker histone, H1, with DNA between nucleosomes facilitates the compaction of chromatin into higher-order structures. Unlike most histone genes, this gene contains introns and its mRNA is polyadenylated. The protein encoded is a replication-independent member of the histone H3 family. Histone variant H3. 3 is typically enriched in active chromatin.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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