Cat.No.: | EAb-1179 |
Product Name: | PSMB2 Polyclonal Antibody, FITC Conjugated |
Antibody Type: | Polyclonal |
Conjugate: | FITC |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Protein G Purified |
Appearance: | Liquid |
Formulation: | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. |
Applications: | ELISA |
Species Reactivity: | Human |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Alternative Name: | Macropain subunit C7-I, Multicatalytic endopeptidase complex subunit C7-I, Proteasome component C7-I |
Scientific Background: | The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB2 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Product Types | ||
◆ Cell Lines | ||
CL-0120 | Human PSMB9 Knockout Cell Line 4bp deletion | Inquiry |
CL-0122 | Human PSMB8 Knockout Cell Line 2bp deletion | Inquiry |
CL-0166 | Human PSG1 Knockout Cell Line | Inquiry |
◆ Proteins & Enzymes | ||
PE-0904 | Recombinant Zebrafish PSME4B | Inquiry |
◆ Antibodies | ||
EAb-1167 | PSMG3 Polyclonal Antibody, HRP Conjugated | Inquiry |
Related Gene / Proteins | |||
PSD3 | PSG1 | PSMA7 | PSMB1 |
PSMB2 | PSMB4 | PSMB7 | PSMB8 |
PSMB9 | PSMC3 | PSMC6 | PSMD10 |
PSMD11 | PSMD2 | PSMD7 | PSME2 |
PSME3 | PSME4B | PSMF1 | PSMG3 |
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