| Cat.No.: | EAb-1181 |
| Product Name: | PSMB2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4. |
| Applications: | ELISA, IF, IHC, WB |
| Recommended Dilutions/Conditions: |
ELISA, WB, IHC, IF; Recommended dilution: IHC:1:100-1:500, IF:1:50-1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | Macropain subunit C7-I, Multicatalytic endopeptidase complex subunit C7-I, Proteasome component C7-I |
| Scientific Background: | The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB2 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0120 | Human PSMB9 Knockout Cell Line 4bp deletion | Inquiry |
| CL-0122 | Human PSMB8 Knockout Cell Line 2bp deletion | Inquiry |
| CL-0166 | Human PSG1 Knockout Cell Line | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0904 | Recombinant Zebrafish PSME4B | Inquiry |
| ◆ Antibodies | ||
| EAb-1167 | PSMG3 Polyclonal Antibody, HRP Conjugated | Inquiry |
| Related Gene / Proteins | |||
| PSD3 | PSG1 | PSMA7 | PSMB1 |
| PSMB2 | PSMB4 | PSMB7 | PSMB8 |
| PSMB9 | PSMC3 | PSMC6 | PSMD10 |
| PSMD11 | PSMD2 | PSMD7 | PSME2 |
| PSME3 | PSME4B | PSMF1 | PSMG3 |
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