| Cat.No.: | EAb-1184 |
| Product Name: | PSMA7 Polyclonal Antibody, HRP Conjugated |
| Antibody Type: | Polyclonal |
| Conjugate: | HRP |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. |
| Applications: | ELISA |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | HSPC, PSMA7, Proteasome subunit RC6-1 Proteasome subunit XAPC7 |
| Scientific Background: | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0120 | Human PSMB9 Knockout Cell Line 4bp deletion | Inquiry |
| CL-0122 | Human PSMB8 Knockout Cell Line 2bp deletion | Inquiry |
| CL-0166 | Human PSG1 Knockout Cell Line | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0904 | Recombinant Zebrafish PSME4B | Inquiry |
| ◆ Antibodies | ||
| EAb-1167 | PSMG3 Polyclonal Antibody, HRP Conjugated | Inquiry |
| Related Gene / Proteins | |||
| PSD3 | PSG1 | PSMA7 | PSMB1 |
| PSMB2 | PSMB4 | PSMB7 | PSMB8 |
| PSMB9 | PSMC3 | PSMC6 | PSMD10 |
| PSMD11 | PSMD2 | PSMD7 | PSME2 |
| PSME3 | PSME4B | PSMF1 | PSMG3 |
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