Cat.No.: | EAb-1197 |
Product Name: | PSME3 Polyclonal Antibody, FITC Conjugated |
Antibody Type: | Polyclonal |
Conjugate: | FITC |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Protein G Purified |
Appearance: | Liquid |
Formulation: | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. |
Applications: | ELISA |
Species Reactivity: | Human |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Alternative Name: | PSME3 , 11S regulator complex subunit gamma, Short name=REG-gamma, Activator of multicatalytic protease subunit 3, Ki nuclear autoantigen, Proteasome activator 28 subunit gamma, PA28g, PA28gamma |
Scientific Background: | Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. |
Product Types | ||
◆ Cell Lines | ||
CL-0120 | Human PSMB9 Knockout Cell Line 4bp deletion | Inquiry |
CL-0122 | Human PSMB8 Knockout Cell Line 2bp deletion | Inquiry |
CL-0166 | Human PSG1 Knockout Cell Line | Inquiry |
◆ Proteins & Enzymes | ||
PE-0904 | Recombinant Zebrafish PSME4B | Inquiry |
◆ Antibodies | ||
EAb-1167 | PSMG3 Polyclonal Antibody, HRP Conjugated | Inquiry |
Related Gene / Proteins | |||
PSD3 | PSG1 | PSMA7 | PSMB1 |
PSMB2 | PSMB4 | PSMB7 | PSMB8 |
PSMB9 | PSMC3 | PSMC6 | PSMD10 |
PSMD11 | PSMD2 | PSMD7 | PSME2 |
PSME3 | PSME4B | PSMF1 | PSMG3 |
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