KLHL2 Polyclonal Antibody, HRP Conjugated


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Cat.No.:  EAb-1311
Product Name:  KLHL2 Polyclonal Antibody, HRP Conjugated
Antibody Type:  Polyclonal
Conjugate:  HRP
Host:  Rabbit
Isotype:  IgG
Purification:  Protein G Purified
Appearance:  Liquid
Formulation:  0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
Applications:  ELISA
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  Kelch-like protein 2, Actin-binding protein Mayven, KLHL2
Scientific Background:  Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation. Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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