| Cat.No.: | EAb-1765 |
| Product Name: | ZNRF3 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Conjugate: | Unconjugated |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4. |
| Applications: | ELISA, IF |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133, RNF203 |
| Scientific Background: | E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0169 | ZNF7 Polyclonal Antibody | Inquiry |
| EAb-0170 | ZNF541 Polyclonal Antibody | Inquiry |
| EAb-0171 | ZNF498 Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0432 | Recombinant Human ZNF295, His-tagged | Inquiry |
| PE-0742 | Recombinant Zebrafish ZNF703 | Inquiry |
| Related Gene / Proteins | |||
| ZNF181 | ZNF295 | ZNF346 | ZNF498 |
| ZNF541 | ZNF576 | ZNF692 | ZNF7 |
| ZNF703 | ZNF74 | ZNF771 | ZNRF3 |
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