N6-Methyladenosine (m6A) Monoclonal Antibody


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Cat.No.:  EAb-1987
Product Name:  N6-Methyladenosine (m6A) Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  This antibody was raised against 6-Methyladenosine conjugated to BSA.
Host:  Mouse
Isotype:  IgG1k
Purification:  Protein A Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  IP; DB
Species Reactivity:  Budding Yeast, Human, Not Species Specific
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  m6A
Scientific Background:  N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3’ UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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