Cat.No.: | EAb-1987 |
Product Name: | N6-Methyladenosine (m6A) Monoclonal Antibody |
Antibody Type: | Monoclonal |
Immunogen: | This antibody was raised against 6-Methyladenosine conjugated to BSA. |
Host: | Mouse |
Isotype: | IgG1k |
Purification: | Protein A Chromatography |
Appearance: | Liquid |
Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
Applications: | IP; DB |
Species Reactivity: | Budding Yeast, Human, Not Species Specific |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Alternative Name: | m6A |
Scientific Background: | N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3’ UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well. |
Product Types | ||
◆ Antibodies | ||
EAb-0260 | N6-Methyladenosine Monoclonal Antibody (17-3-4-1) | Inquiry |
EAb-1987 | N6-Methyladenosine (m6A) Monoclonal Antibody | Inquiry |
EAb-1988 | N6-Methyladenosine (m6A) Polyclonal Antibody | Inquiry |
◆ Research Kits | ||
EKIT-0311 | m6A RNA Methylation Assay Kit (Colorimetric) | Inquiry |
Related Gene / Proteins | |||
m6A |
USA
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