BCL11A / CTIP1 Polyclonal Antibody


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Cat.No.:  EAb-2052
Product Name:  BCL11A / CTIP1 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This BCL11A / CTIP1 antibody was raised against a peptide within the N-terminal region of human BCL11A / CTIP1.
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  130 kDa
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide.
Applications:  IP: 5 - 10 µl per IP; WB: 1:1,000 - 1:5,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  BCL11A / CTIP1 (B-cell CLL/lymphoma 11A, COUP-TF-interacting protein 1) is a transcriptional regulator, a myeloid and B-cell proto-oncogene and plays important roles in leukemogenesis and hematopoiesis. BCL11A / CTIP1 is involved in regulating hemoglobin gene expression. BCL11A regulates hemoglobin gene switching during fetal development and silencing of γ-globin expression in adults. BCL11A interacts with the Mi-2/NuRD chromatin remodeling complexes, as well as the erythroid transcription factors GATA1 and FOG1. Abundant expression of full-length forms of BCL11A is developmentally restricted to adult erythroid cells.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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