Cat.No.: | EAb-2052 |
Product Name: | BCL11A / CTIP1 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | This BCL11A / CTIP1 antibody was raised against a peptide within the N-terminal region of human BCL11A / CTIP1. |
Host: | Rabbit |
Isotype: | IgG |
Molecular Weight: | 130 kDa |
Purification: | Affinity Purified |
Appearance: | Liquid |
Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
Applications: | IP: 5 - 10 µl per IP; WB: 1:1,000 - 1:5,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Scientific Background: | BCL11A / CTIP1 (B-cell CLL/lymphoma 11A, COUP-TF-interacting protein 1) is a transcriptional regulator, a myeloid and B-cell proto-oncogene and plays important roles in leukemogenesis and hematopoiesis. BCL11A / CTIP1 is involved in regulating hemoglobin gene expression. BCL11A regulates hemoglobin gene switching during fetal development and silencing of γ-globin expression in adults. BCL11A interacts with the Mi-2/NuRD chromatin remodeling complexes, as well as the erythroid transcription factors GATA1 and FOG1. Abundant expression of full-length forms of BCL11A is developmentally restricted to adult erythroid cells. |
Product Types | ||
◆ Extracts & Lysates | ||
EL-0087 | Recombinant Human BCOR 293 Cell Lysate | Inquiry |
◆ Proteins & Enzymes | ||
PE-0708 | Recombinant Human BCOR, GST-tagged | Inquiry |
PE-0709 | Recombinant Zebrafish BCOR | Inquiry |
PE-0710 | Recombinant Mouse BCOR Protein | Inquiry |
PE-0711 | Recombinant Human BCOR Protein, GST-tagged | Inquiry |
Related Gene / Proteins | |||
Bcl10 | BCL11A | Bcl3 | Bcl6 |
BCOR |
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