Cat.No.: | EAb-2108 |
Product Name: | JMJD6 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | This antibody was raised against a peptide within the N-terminal region of human JMJD6. |
Host: | Rabbit |
Isotype: | IgG |
Molecular Weight: | 52 kDa |
Purification: | Affinity Purified |
Appearance: | Liquid |
Formulation: | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
Applications: | WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Scientific Background: | JMJD6 (Jumonji Domain-Containing Protein 6) is a dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. JMJD6 acts as an arginine demethylase which demethylates histone H3 at 'Arg-2' (H3R2me) and histone H4 at 'Arg-3' (H4R3me), thereby playing a role in histone code. Required for differentiation of multiple organs during embryogenesis and acts as a key regulator of hematopoietic differentiation. May act as a RNA hydroxylase, as suggested by its ability to bind single strand RNA. |
Product Types | ||
◆ Bioactive Small Molecules | ||
BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
◆ Antibodies | ||
EAb-0072 | JMJD6 Polyclonal Antibody | Inquiry |
EAb-0074 | JMJD2c Polyclonal Antibody | Inquiry |
EAb-0075 | JMJD2b Polyclonal Antibody | Inquiry |
EAb-0076 | JMJD2A Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
JMJD | JMJD1A | JMJD1B | JMJD1C |
JMJD2 | JMJD2A | JMJD2B | JMJD2C |
JMJD2D | JMJD2E | JMJD2F | JMJD3 |
JMJD4 | JMJD5 | JMJD6 |
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