ING1 Monoclonal Antibody


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Cat.No.:  EAb-2155
Product Name:  ING1 Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  This antibody was raised against a recombinant protein corresponding to amino acids 67 - 279 of human ING1.
Host:  Mouse
Isotype:  IgG2a
Molecular Weight:  47 kDa
Purification:  Protein A Chromatography
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  ICC/IF; WB
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  ING1 (Inhibitor Of Growth Family, Member 1) is a member of the inhibitor of growth (ING) family of proteins that play key roles in cell cycle arrest, apoptosis, cell aging, and the DNA damage response. ING1 contains a PHD domain that interacts with Histone H3K4me3. ING1 cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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