Histone H3K56me2 Polyclonal Antibody


  • Specification
  • Target Information
  • Related Products
Cat.No.:  EAb-2204
Product Name:  Histone H3K56me2 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This Histone H3 dimethyl Lys56 antibody was raised against a peptide including dimethyl-lysine 56 of human histone H3.
Host:  Rabbit
Isotype:  Serum
Molecular Weight:  17 kDa
Purification:  None
Appearance:  Liquid
Formulation:  Rabbit serum containing 30% glycerol and 0.035% sodium azide.
Applications:  WB: 1:5,000 - 1:20,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Wide Range Predicted
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Histone H3 is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; these modifications play a major role in regulating gene expression.The methylation of histones can occur on two different residues: arginine or lysine. Histone methylation can be associated with transcriptional activation or repression, depending on the methylated residue. Lysine 56 of histone H3 can be mono-, di- or trimethylated by different histone methyltransferases (HMTs).

Online Inquiry

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

USA

Enter your email here to subscribe.

Follow us on

Easy access to products and services you need from our library via powerful searching tools

Copyright © Creative BioMart. All Rights Reserved.