Histone H3R17me2a (asymmetric) Polyclonal Antibody


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Cat.No.:  EAb-2227
Product Name:  Histone H3R17me2a (asymmetric) Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This Histone H3 dimethyl Arg17 asymmetric antibody was raised against a peptide containing dimethyl-Arg17 (asymmetric) of human histone H3.
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  17 kDa
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide.
Applications:  WB: 1:500 - 1:2,000 dilution; ChIP; WBIHC (FFPE)IF^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Wide Range Predicted
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Histones are subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; these modifications play a major role in regulating gene expression. The methylation of histones can occur on two different residues: arginine or lysine.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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