Histone H3R8me1 Polyclonal Antibody


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Cat.No.:  EAb-2242
Product Name:  Histone H3R8me1 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This Histone H3 monomethyl Arg8 antibody was raised against a peptide containing monomethyl-Arg8 of human histone H3.
Host:  Rabbit
Isotype:  Serum
Molecular Weight:  17 kDa
Purification:  None
Appearance:  Liquid
Formulation:  Rabbit serum containing 30% glycerol and 0.035% sodium azide.
Applications:  WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Wide Range Predicted
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Histones are subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; these modifications play a major role in regulating gene expression. The methylation of histones can occur on two different residues: arginine or lysine. Histone H3 Arg8, methylated by PRMT enzymes, is involved in nuclear-receptor-mediated transcriptional activation.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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