Histone H2AS129ph Polyclonal Antibody


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Cat.No.:  EAb-2275
Product Name:  Histone H2AS129ph Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This Histone H2A phospho Ser129 antibody was raised against a peptide including phospho-serine 129 of budding yeast Histone H2A.
Host:  Rabbit
Isotype:  Serum
Molecular Weight:  14 kDa
Purification:  None
Appearance:  Liquid
Formulation:  Rabbit serum containing 30% glycerol and 0.035% sodium azide.
Applications:  WB: 1:500 - 1:2,000 dilution; ChIP^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Budding Yeast, Wide Range Predicted
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  Histone H2A is one of the core components of the nucleosome, the basic building block of chromatin. Unlike mammals that have a distinct DNA damage-responsive histone H2A variant, H2AX, budding yeast histone H2A contains an SQ motif in the C-terminus that is phosphorylated by the Mec1 and Tel1 kinases in response to DNA double strand breaks. As with mammalian H2AX phosphorylation, phosphorylation of yeast histone H2A at serine 129 is required for the efficient repair of DNA double-strand breaks.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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