| Cat.No.: | EAb-2289 |
| Product Name: | Acetyl-Histone Recombinant Antibody |
| Antibody Type: | Recombinant |
| Immunogen: | Acetyllysine-BSA |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein A Chromatography |
| Appearance: | Liquid |
| Formulation: | PBS containing 50% Glycerol, 1% BSA, and 0.09% sodium azide. |
| Applications: | WB: 0.5 - 2 µg/ml; ICC: 2 - 10 µg/ml^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Not Species Specific |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | Lysine N-acetylation is a dynamic, reversible and tightly regulated protein and histone modification that plays a major role in chromatin remodeling and in the regulation of gene expression in various cellular functions. Acetylation of histones can occur at several different lysine positions in the histone tail, and is performed by Histone Acetyltransferases (HATs) such as HAT1 or GCN5. Acetylation of histones is often associated with transcriptional activation.Clone RM101 reacts to lysine-acetylated proteins. No cross reactivity with nonacetylated lysine, and lysines with other modifications. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0007 | Recombinant Tetranucleosomes H3.3 | Inquiry |
| NUC-0008 | Recombinant Mononucleosomes H3.3 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0009 | Histone H4 peptide (1-21), Biotin-labeled | Inquiry |
| SP-0010 | Histone H4 peptide (1-21) | Inquiry |
| SP-0012 | Histone H3 peptide (21-44), Biotin-labeled | Inquiry |
| Related Gene / Proteins | |||
| HIC1 | HIF1A | HIF1AN | HINFP |
| HIPK1 | HIPK2 | HIRA | Histone |
| Histone H1 | Histone H2A | Histone H2B | Histone H3 |
| Histone H4 | HIV-1 reverse transcriptase | ||
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