Cat.No.: | EAb-2318 |
Product Name: | PRMT6 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | This PRMT6 antibody was raised against a peptide corresponding to amino acids within the N-terminal region of PRMT6. |
Host: | Rabbit |
Isotype: | IgG |
Molecular Weight: | 42 kDa |
Purification: | Affinity Purified |
Appearance: | Liquid |
Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
Applications: | WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Scientific Background: | PRMT6 (Protein Arginine Methyltransferase 6, HRMT1L6, ANM6) is a type I arginine methyltransferase. Arginine methylation is a common post-translational modification of histones and other cellular proteins. PRMT6 preferentially methylates arginine residues present in GAR (glycine and arginine-rich) domains. PRMT6 asymmetrically dimethylates histone H3 at Arg2, which is mutually exclusive to methylation at lysine 4 (associated with transcriptional activation), and thus PRMT6 serves as a transcriptional repressor in this context. It can also symmetrically dimethylate H2A and H4 at Arg3 and serves as a coactivator of transcription in concert with nuclear receptors. |
Product Types | ||
◆ Bioactive Small Molecules | ||
BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
BSM-0047 | SGC707 | Inquiry |
◆ Antibodies | ||
EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
Pr-SET7 | PRC1 | PRC2 | PRDM1 |
PRDM10 | PRDM11 | PRDM12 | PRDM13 |
PRDM14 | PRDM15 | PRDM16 | PRDM17 |
PRDM2 | PRDM3 | PRDM4 | PRDM5 |
PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
PREP1 | PRIM2 | PRKAA2 | PRKCA |
PRKCB | PRKCE | PRKDC | PRKRIP1 |
PRMT | prmt1 | PRMT2 | PRMT3 |
PRMT5 | prmt6 | PRMT7 | PRMT8 |
PRMT9 | Progerin | Protamine 2 | Prox1 |
PRPF31 | PRPF40A | PRSS12 | PRSS55 |
PRTFDC1 |
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