| Cat.No.: | EAb-2503 |
| Product Name: | KAT13A/SRC1 Polyclonal Antibody - ChIP Grade |
| Product Overview: | Rabbit polyclonal to detect KAT13A/SRC1 - ChIP Grade |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to Human KAT13A/ SRC1 aa 8-24. |
| Immunogen Sequence: | SSDPANPDSHKRKGSPC |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | 0.05% Sodium azide, 0.1% BSA, 99% PBS |
| Applications: | IHC-Fr, IHC-P, Flow Cyt, ChIP, ICC/IF |
| Species Reactivity: | Mouse, Rat, Chicken, Human, Bird |
| Storage: | -20°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q15788 |
| Alternative Name: | bHLHe74 antibody/Class E basic helix-loop-helix protein 74 antibody/F SRC 1 antibody |
| Scientific Background: | Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3. |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0073 | Anacardic Acid | Inquiry |
| ◆ Antibodies | ||
| EAb-0073 | KAT8 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0083 | Human KAT2A Knockout Cell Line 1bp insertion | Inquiry |
| CL-0085 | Human KAT2B Knockout Cell Line 31bp deletion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0159 | Recombinant Human MYST2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| Kaiso | KANSL2 | KAP1 | KAT13A |
| KAT13D | KAT2A | KAT2B | KAT4 |
| KAT5 | KAT6A | KAT6B | KAT7 |
| KAT8 | KAT9 | SRBD1 | SRC1 |
| SREBP | SREBP-1 | SREBP-2 | SRF More > |
| SRP14 | SRP19 | SRY | |
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