KAT2B/PCAF Polyclonal Antibody - ChIP Grade


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Cat.No.:  EAb-2504
Product Name:  KAT2B/PCAF Polyclonal Antibody - ChIP Grade
Product Overview:  Rabbit polyclonal to detect KAT2B/PCAF - ChIP Grade
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide with N-terminal added cysteine conjugated to KLH, corresponding to the C-terminal amino acids 817-832 of Human PCAF.
Immunogen Sequence:  EKFFFSKIKEAGLIDK
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  pH: 7.40; 0.097% Sodium azide, 0.0268% PBS, 1% BSA
Applications:  IHC-P, ChIP, WB, IP, ICC/IF
Species Reactivity:  Mouse, Dog, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  CAF antibody/CREBBP associated factor antibody/GCN5 antibody
Scientific Background:  Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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