Cat.No.: | EAb-2558 |
Product Name: | EZH1 Polyclonal Antibody |
Product Overview: | Rabbit polyclonal to detect EZH1 |
Antibody Type: | Polyclonal |
Immunogen: | Synthetic peptide (Human) from an internal region of EZH1. |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Immunogen affinity purified |
Appearance: | Liquid |
Formulation: | pH: 7.40; 0.02% Sodium azide, PBS, 50% Glycerol, 0.87% Sodium chloride (PBS without Mg2+ and Ca2+) |
Applications: | WB, IHC-P, ELISA |
Species Reactivity: | Mouse, Human |
Storage: | -20°C. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | Q92800 |
Alternative Name: | Enhancer of zeste homolog 1 (Drosophila) antibody/Enhancer of zeste homolog 1 antibody/ENX-2 antibody |
Scientific Background: | Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
Product Types | ||
◆ Bioactive Small Molecules | ||
BSM-0006 | GSK343 | Inquiry |
BSM-0059 | 3-Deazaneplanocin A | Inquiry |
BSM-0060 | 3-Deazaneplanocin A hydrochloride | Inquiry |
◆ Extracts & Lysates | ||
EL-0024 | Recombinant Human EZH1 293 Cell Lysate | Inquiry |
EL-0025 | Recombinant Human EZH2 293 Cell Lysate | Inquiry |
Related Gene / Proteins | |||
ezh1 | EZH2 |
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