KMT3A/HYPB/HIF-1 Polyclonal Antibody


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Cat.No.:  EAb-2572
Product Name:  KMT3A/HYPB/HIF-1 Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect KMT3A/HYPB/HIF-1
Antibody Type:  Polyclonal
Immunogen:  A region within synthetic peptide corresponding to N terminal amino acids 577-626 of Human KMT3A/ HYPB/ HIF-1
Immunogen Sequence:  ELNEEIKQSH SFSLQTPCSK GSELRMINKN PEREKAGSPA PSNRLNDSPT
Host:  Rabbit
Isotype:  IgG
Purification:  Protein A purified
Appearance:  Liquid
Formulation:  0.09% Sodium azide, 2% Sucrose, PBS
Applications:  ICC/IF, WB, IHC-P
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  EC 2.1.1.43 antibody/FLJ16420 antibody/FLJ22472 antibody
Scientific Background:  Histone methyltransferase that methylates 'Lys-36' of histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. Probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. Binds DNA at promoters. May also act as a transcription activator that binds to promoters. Binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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