KMT2D/MLL2 Polyclonal Antibody


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Cat.No.:  EAb-2594
Product Name:  KMT2D/MLL2 Polyclonal Antibody
Product Overview:  Goat polyclonal to detect KMT2D/MLL2
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to Human KMT2D/ MLL2 aa 2-14 (N terminal).
Immunogen Sequence:  DSQNLAGEDKDSQ-C
Host:  Goat
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  0.02% Sodium Azide
Applications:  IHC-P
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  O14688; Entrez gene ID: 8085
Alternative Name:  AAD10 antibody/ALL1 related gene antibody/ALL1-related protein antibody
Scientific Background:  Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.
Product Types
◆ Bioactive Small Molecules
BSM-0170 MI-3 Inquiry
BSM-0187 OICR-9429 Inquiry
◆ Synthetic Peptides
SP-0172 Human KMT2C / MLL3 peptide Inquiry
◆ Cell Lines
CL-0216 Human KMT2A Knockout Cell Line 32bp deletion Inquiry
◆ Research Kits
EKIT-0285 MLL1 Complex Chemiluminescent Assay Kit Inquiry
Related Gene / Proteins
KMT1B KMT1E KMT2A KMT2B
KMT2C KMT2D KMT2E KMT3A
KMT3B KMT3C KMT5A KMT6
MLH1 MLL mll1 MLL2
MLL3 MLL4 MLL5 MLLT1 More >
MLLT3

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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