ING2 Polyclonal Antibody


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Cat.No.:  EAb-2646
Product Name:  ING2 Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect ING2
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide conjugated to KLH derived from within residues 250 to the C-terminus of Human ING2.
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  pH: 7.40; 0.02% Sodium azide, PBS
Applications:  ICC/IF, WB
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  ING 1 like tumor suppressor protein antibody/ING 1L antibody/ING 2 antibody
Scientific Background:  Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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