NCOR2/SMRT Monoclonal Antibody (1542)


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Cat.No.:  EAb-2711
Product Name:  NCOR2/SMRT Monoclonal Antibody (1542)
Product Overview:  Mouse monoclonal (1542) to detect NCOR2/SMRT
Antibody Type:  Monoclonal
Clone Designation:  1542
Immunogen:  Synthetic peptide corresponding to Human NCOR2/SMRT aa 994-1005.
Immunogen Sequence:  CGGA-SASDPHREKTQ
Host:  Mouse
Isotype:  IgG1
Purification:  Affinity purified
Appearance:  Liquid
Formulation:  0.05% Sodium azide, 0.1% BSA, 99% PBS
Applications:  ChIP, IHC-Fr, WB, Flow Cyt, IP, IHC-P
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  CTG 26 antibody/CTG repeat protein 26 antibody/CTG26 antibody
Scientific Background:  Transcriptional corepressor of NR4A2/NURR1 and acts through histone deacetylases (HDACs) to keep promoters of NR4A2/NURR1 target genes in a repressed deacetylated state (By similarity). Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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