HIF1AN/FIH-1 Polyclonal Antibody


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Cat.No.:  EAb-2720
Product Name:  HIF1AN/FIH-1 Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect HIF1AN/FIH-1
Antibody Type:  Polyclonal
Immunogen:  Recombinant fragment within Human HIF1AN/FIH-1 (internal sequence).
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  pH: 7.00; 0.01% Thimerosal (merthiolate), PBS, 20% Glycerol
Applications:  WB, IHC-P, ICC/IF
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q9NWT6
Alternative Name:  DKFZp762F1811 antibody/Factor inhibiting HIF-1 antibody/Factor inhibiting HIF1 antibody
Scientific Background:  Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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