Cat.No.: | EAb-2905 |
Product Name: | gamma H2A.X pS139 Polyclonal Antibody |
Product Overview: | Rabbit polyclonal to detect gamma H2A.X (phospho S139) |
Antibody Type: | Polyclonal |
Immunogen: | Synthetic peptide corresponding to Human gamma H2A.X (phospho S139). |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Immunogen affinity purified |
Appearance: | Liquid |
Formulation: | 0.1% Sodium azide, 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris |
Applications: | IHC-P, ICC/IF, WB, Flow Cyt, ICC |
Species Reactivity: | Mouse, Chicken, Human, Dictyostelium discoideum |
Storage: | -20°C. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | 3014 |
Alternative Name: | H2A histone family member X antibody/H2A histone family member X antibody/H2A.FX antibody |
Scientific Background: | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. |
Product Types | ||
◆ Nucleosomes | ||
NUC-0020 | Recombinant Nucleosome, H2AR3me1 dNuc | Inquiry |
NUC-0021 | Recombinant Nucleosome, H2AR3me2a dNuc | Inquiry |
NUC-0075 | Recombinant Nucleosome, H2AK119ub dNuc | Inquiry |
NUC-0076 | Recombinant Nucleosome, H2BK120ub dNuc | Inquiry |
NUC-0082 | Recombinant Nucleosome, H2AXS139phos dNuc | Inquiry |
Related Gene / Proteins | |||
H2AK11 | H2AK119 | H2AK12 | H2AK13 |
H2AK15 | H2AK16 | H2AK4 | H2AK5 |
H2AK7 | H2AK8 | H2AK9 | H2AP26 |
H2AQ104 | H2AR29 | H2AR3 | H2AS1 |
H2AS129 | H2AS139 | H2AS2 | H2AT120 More > |
H2AT121 | H2AT142 | H2AY142 | H2BK108 |
H2BK11 | H2BK116 | H2BK12 | H2BK120 |
H2BK126 | H2BK15 | H2BK16 | H2BK20 |
H2BK23 | H2BK43 | H2BK46 | H2BK5 |
H2BR79 | H2BS112 | H2BS14 | H2BS32 |
H2BT129 |
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