Histone H3R17me2a/K18ac Polyclonal Antibody


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Cat.No.:  EAb-3056
Product Name:  Histone H3R17me2a/K18ac Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect Histone H3 (asymmetric di methyl R17, acetyl K18)
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to Human Histone H3 (asymmetric di methyl R17, acetyl K18) conjugated to keyhole limpet haemocyanin.
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purified
Appearance:  Liquid
Formulation:  0.05% Sodium azide, 0.05% Proclin, PBS
Applications:  Western blot, IF, ELISA, Dot Blot, ChIP.
Recommended Dilutions/Conditions:  WB: 1:1000, Dot Blot: 1:20,000, ChIP: 1 µl/ChIP, IF: 1:500, ELISA: 1:1000.
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Mouse, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  P68431
Alternative Name:  H3 histone family member E pseudogene antibody/H3 histone family, member A antibody/H3/A antibody
Scientific Background:  Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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