Histone H2A.Z K7ac Monoclonal Antibody (RM222)


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Cat.No.:  EAb-3067
Product Name:  Histone H2A.Z K7ac Monoclonal Antibody (RM222)
Product Overview:  Rabbit monoclonal (RM222) to detect Histone H2A.Z (acetyl K7)
Antibody Type:  Monoclonal
Clone Designation:  RM222
Immunogen:  Synthetic peptide corresponding to Human Histone H2A.Z (acetyl K7).
Host:  Rabbit
Isotype:  IgG
Purification:  Protein A purified
Appearance:  Liquid
Formulation:  0.09% Sodium azide, 50% Glycerol, 1% BSA, 48% PBS
Applications:  ELISA, ICC/IF, WB
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  P0C0S5
Alternative Name:  H2A histone family member Z antibody/H2A.z antibody/H2A/z antibody
Scientific Background:  Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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