Dnmt3L Polyclonal Antibody


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Cat.No.:  EAb-3167
Product Name:  Dnmt3L Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect Dnmt3L
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to Human Dnmt3L aa 152-164 conjugated to keyhole limpet haemocyanin.
Immunogen Sequence:  C-GLLQRRRKWRSQL
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  pH: 7.20; 0.01% Sodium azide, 0.42% Potassium phosphate, 0.87% Sodium chloride
Applications:  ICC/IF, ELISA, WB, IP
Species Reactivity:  Mouse, Rat, Hamster, Cow, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q9UJW3
Alternative Name:  Cytosine 5 methyltransferase 3 like protein antibody/DNA (cytosine 5 ) methyltransferase 3 like antibody/DNA (cytosine-5)-methyltransferase 3-like antibody
Scientific Background:  Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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