| Cat.No.: | EAb-3314 |
| Product Name: | Histone γH2A.X pS139 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | A synthetic phosphorylated peptide around S139 of human γH2A.X |
| Immunogen Sequence: | TQASQ |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 17kDa |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB; IHC; IF |
| Recommended Dilutions/Conditions: |
WB: 1:500 - 1:1000; IHC: 1:50 - 1:100 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | Jurkat,NIH/3T3,C6 |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20℃. |
| Storage Buffer: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Swiss Prot P16104; NP_002096.1; Gene ID 3014 |
| Alternative Name: | H2AFX; H2A.X; H2A/X; H2AX; histone H2AX;γH2AX;gamma H2AX;gamma H2A.X (phospho S139); |
| Scientific Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0020 | Recombinant Nucleosome, H2AR3me1 dNuc | Inquiry |
| NUC-0021 | Recombinant Nucleosome, H2AR3me2a dNuc | Inquiry |
| NUC-0075 | Recombinant Nucleosome, H2AK119ub dNuc | Inquiry |
| NUC-0076 | Recombinant Nucleosome, H2BK120ub dNuc | Inquiry |
| NUC-0082 | Recombinant Nucleosome, H2AXS139phos dNuc | Inquiry |
| Related Gene / Proteins | |||
| H2AK11 | H2AK119 | H2AK12 | H2AK13 |
| H2AK15 | H2AK16 | H2AK4 | H2AK5 |
| H2AK7 | H2AK8 | H2AK9 | H2AP26 |
| H2AQ104 | H2AR29 | H2AR3 | H2AS1 |
| H2AS129 | H2AS139 | H2AS2 | H2AT120 More > |
| H2AT121 | H2AT142 | H2AY142 | H2BK108 |
| H2BK11 | H2BK116 | H2BK12 | H2BK120 |
| H2BK126 | H2BK15 | H2BK16 | H2BK20 |
| H2BK23 | H2BK43 | H2BK46 | H2BK5 |
| H2BR79 | H2BS112 | H2BS14 | H2BS32 |
| H2BT129 | |||
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