Histone H4K16ac Polyclonal Antibody


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Cat.No.:  EAb-3396
Product Name:  Histone H4K16ac Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  A synthetic acetylated peptide around K16 of human Histone H4
Immunogen Sequence:  GGAKR
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  13kDa
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB; IF; ChIP
Recommended Dilutions/Conditions:  WB: 1:500 - 1:2000; ChIP: 1:50 - 1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  Hela TSA,HeLa,C2C12 TSA,C2C12
Species Reactivity:  Human, Mouse, Rat
Storage:  -20℃.
Storage Buffer:  PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Swiss Prot P62805; NP_001029249.1; Gene ID 8370
Alternative Name:  HIST2H4A; FO108; H4; H4/n; H4F2; H4FN; HIST2H4; histone H4
Scientific Background:  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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