Cat.No.: | EAb-3426 |
Product Name: | PRMT6 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-375 of human PRMT6 |
Immunogen Sequence: | MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQEEKTKDFAMED |
Host: | Rabbit |
Isotype: | IgG |
Molecular Weight: | 42kDa |
Purification: | Affinity purification |
Appearance: | Liquid |
Applications: | WB; IF |
Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Positive Control: | HeLa,SKOV3,MCF7 |
Species Reactivity: | Human, Mouse |
Storage: | -20℃. |
Storage Buffer: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | Swiss Prot Q96LA8; NP_060607.2; Gene ID 55170 |
Alternative Name: | PRMT6; HRMT1L6; protein arginine methyltransferase 6 |
Scientific Background: | The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. |
Product Types | ||
◆ Bioactive Small Molecules | ||
BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
BSM-0047 | SGC707 | Inquiry |
◆ Antibodies | ||
EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
Pr-SET7 | PRC1 | PRC2 | PRDM1 |
PRDM10 | PRDM11 | PRDM12 | PRDM13 |
PRDM14 | PRDM15 | PRDM16 | PRDM17 |
PRDM2 | PRDM3 | PRDM4 | PRDM5 |
PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
PREP1 | PRIM2 | PRKAA2 | PRKCA |
PRKCB | PRKCE | PRKDC | PRKRIP1 |
PRMT | prmt1 | PRMT2 | PRMT3 |
PRMT5 | prmt6 | PRMT7 | PRMT8 |
PRMT9 | Progerin | Protamine 2 | Prox1 |
PRPF31 | PRPF40A | PRSS12 | PRSS55 |
PRTFDC1 |
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