| Cat.No.: | PE-0217 |
| Product Name: | Recombinant Human EZH1 protein, His-tagged |
| Product Overview: | Recombinant Human EZH1 aa. (Pro559~Leu747) fused with N-terminal His tag was produced in E. coli cells. |
| Description: | EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]). |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Freeze-dried powder |
| Molecular Weight: | 25kDa as determined by SDS-PAGE reducing conditions. |
| Purity: | >95% |
| Species: | Human |
| Tag: | His |
| Endotoxin: | <1.0EU per 1ug (determined by the LAL method) |
| Reconstitution: | Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
| Expression System: | E. coli |
| Isoelectric Point: | The isoelectric point is 8.1. |
| Protein Length: | Pro559~Leu747 |
| Concentrations: | 200μg/mL |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit [ Homo sapiens (human) ] |
| Gene ID NCBI: | 2145 |
| Official Symbol: | EZH1 |
| Synonyms: | EZH1; enhancer of zeste 1 polycomb repressive complex 2 subunit; KMT6B; histone-lysine N-methyltransferase EZH1; ENX-2; enhancer of zeste homolog 1 |
| mRNA Refseq: | NM_001321079.1 |
| Protein Refseq: | NP_001308008.1 |
| UniProt ID: | Q92800 |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0006 | GSK343 | Inquiry |
| BSM-0059 | 3-Deazaneplanocin A | Inquiry |
| BSM-0060 | 3-Deazaneplanocin A hydrochloride | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0024 | Recombinant Human EZH1 293 Cell Lysate | Inquiry |
| EL-0025 | Recombinant Human EZH2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| ezh1 | EZH2 | ||
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