| Cat.No.: | PE-0249 |
| Product Name: | Recombinant Human EED, His-tagged |
| Product Overview: | Recombinant EED protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Description: | EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta 7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function.? |
| Applications: | SDS-PAGE |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 52.6kDa (464aa) |
| Purity: | >85% by SDS - PAGE |
| Species: | Human |
| Formulation: | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSEREVS TAPAGTDMPA AKKQKLSSDE NSNPDLSGDE NDDAVSIESG TNTERPDTPT NTPNAPGRKS WGKGKWKSKK CKYSFKCVNS LKEDHNQPLF GVQFNWHSKE GDPLVFATVG SNRVTLYECH SQGEIRLLQS YVDADADENF YTCAWTYDSN TSHPLLAVAG SRGIIRIINP ITMQCIKHYV GHGNAINELK FHPRDPNLLL SVSKDHALRL WNIQTDTLVA IFGGVEGHRD EVLSADYDLLGEKIMSCGMD HSLKLWRINS KRMMNAIKES YDYNPNKTNR PFISQKIHFP DFSTRDIHRN YVDCVRWLGD LILSKSCENA IVCWKPGKME DDIDKIKPSE SNVTILGRFD YSQCDIWYMR FSMDFWQKML ALGNQVGKLY VWDLEVEDPH KAKCTTLTHH KCGAAIRQTS FSRDSSILIA VCDDASIWRW DRLR |
| Expression System: | E. coli |
| Protein Length: | 1-441aa |
| Concentrations: | 1 mg/ml |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | EED embryonic ectoderm development [ Homo sapiens ] |
| Gene ID NCBI: | 8726 |
| Synonyms: | EED; embryonic ectoderm development; polycomb protein EED; HEED; WAIT 1; WD protein associating with integrin cytoplasmic tails 1; WAIT1; |
| mRNA Refseq: | NM_003797 |
| Protein Refseq: | NP_003788 |
| MIM: | 605984 |
| UniProt ID: | O75530 |
| Chromosome Location: | 11q14.2-q22.3 |
| Function: | chromatin binding; histone methyltransferase activity; identical protein binding; protein binding; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0026 | Recombinant Human EED Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0166 | MAK-683 | Inquiry |
| ◆ Research Kits | ||
| EKIT-0182 | EZH2-EED Binding Assay Kit | Inquiry |
| ◆ Antibodies | ||
| EAb-0196 | EEF1A Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0248 | Recombinant Human EED, His & GST tagged | Inquiry |
| Related Gene / Proteins | |||
| EED | EEF1A1 | EEF1A2 | EEF1B2 |
| EEF1G | |||
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