| Cat.No.: | PE-0368 |
| Product Name: | Recombinant Human BRDT, His-tagged |
| Product Overview: | Recombinant protein includes Bromo 1 domain (22-138 aa) with N-terminal His-tag. |
| Description: | BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 13.9 kDa (117aa, 22-138 +NT-His Tag) |
| Purity: | ≥98% by SDS-PAGE |
| Species: | Human |
| Formulation: | rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol. |
| Tag: | His |
| Expression System: | E. coli |
| Protein Length: | 22-138 aa |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | BRDT bromodomain, testis-specific [ Homo sapiens (human) ] |
| Gene ID NCBI: | 676 |
| Synonyms: | BRDT; bromodomain, testis-specific; CT9; BRD6; bromodomain testis-specific protein; RING3-like protein; cancer/testis antigen 9 |
| mRNA Refseq: | NM_001726 |
| Protein Refseq: | NP_001717 |
| MIM: | 602144 |
| UniProt ID: | Q58F21 |
| Chromosome Location: | 1p22.1 |
| Function: | histone acetyl-lysine binding; histone binding; transcription coactivator activity |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0001 | Bromodomain Non-Acetylated Ligand 4 | Inquiry |
| SP-0002 | Bromodomain Non-Acetylated Ligand 3 | Inquiry |
| SP-0003 | Bromodomain Non-Acetylated Ligand 1 | Inquiry |
| SP-0004 | Bromodomain Ligand 3 | Inquiry |
| SP-0006 | Bromodomain Ligand 4 | Inquiry |
| Related Gene / Proteins | |||
| BRCA1 | BRCA2 | BRCC3 | BRD |
| brd1 | brd2 | brd3 | brd4 |
| BRD7 | BRD8 | brd9 | brdt |
| BRL | BRM | BRMS1 | BRPF1 |
| BRPF2 | brpf3 | BRWD1 | BRWD3 |
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