| Cat.No.: | PE-0502 |
| Product Name: | Recombinant Rat Mitogen-activated Protein Kinase 8 |
| Product Overview: | Recombinant rat Mapk8 is expressed in E. coli. |
| Description: | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid. |
| Molecular Weight: | 48000Da. |
| Purity: | ≥90% by SDS-PAGE. |
| Species: | Rat |
| Activity: | ≥30 units/mg protein. |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | Mapk8 mitogen-activated protein kinase 8 [ Rattus norvegicus ] |
| Gene ID NCBI: | 116554 |
| Synonyms: | Mapk8; mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; SAPK gamma; c-Jun N-terminal kinase 1; c-jun NH2-terminal kinase; p54 gamma; stress-activated protein kinase JNK1; JNK |
| mRNA Refseq: | XM_341399 |
| Protein Refseq: | XP_341400 |
| UniProt ID: | P49185 |
| Chromosome Location: | 16p16 |
| Function: | ATP binding; JUN kinase activity; MAP kinase activity; protein serine/threonine kinase activity; transferase activity |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0025 | Human MAGI1 Knockout Cell Line | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0058 | Recombinant Human MAPK8 293 Cell Lysate | Inquiry |
| EL-0059 | Recombinant Human MAPK8 293 Cell Lysate | Inquiry |
| EL-0074 | Recombinant Human MAGEA2 293 Cell Lysate | Inquiry |
| EL-0096 | Recombinant Human MACROD2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| MACROD2 | MAF | MAFF | MAGEA2 |
| MAGI1 | MAGOH | MAK16 | MALT1 |
| MAPK8 | MASH1 | MASP1 | Mat2A |
| MATR3 | MAX | MAZ | |
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