| Cat.No.: | PE-0510 |
| Product Name: | Recombinant Human MAPK8, His-tagged |
| Product Overview: | Recombinant human MAPK8, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Description: | MAPK8 also known as mitogen-activated protein kinase 8 JNK beta 2. MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 50.5kDa (450aa) |
| Purity: | >85% by SDS - PAGE |
| Species: | Human |
| Formulation: | Liquid. In Phosphate Buffer Saline (pH7.4) containing 20% glycerol, 1mM DTT |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSRSKRD NNFYSVEIGD STFTVLKRYQ NLKPIGSGAQ GIVCAAYDAI LERNVAIKKL SRPFQNQTHA KRAYRELVLM KCVNHKNIIG LLNVFTPQKS LEEFQDVYIV MELMDANLCQ VIQMELDHER MSYLLYQMLC GIKHLHSAGI IHRDLKPSNI VVKSDCTLKI LDFGLARTAG TSFMMTPYVV TRYYRAPEVI LGMGYKENVD IWSVGCIMGE MIKGGVLFPG TDHIDQWNKV IEQLGTPCPE FMKKLQPTVR TYVENRPKYA GYSFEKLFPD VLFPADSEHN KLKASQARDL LSKMLVIDAS KRISVDEALQ HPYINVWYDP SEAEAPPPKI PDKQLDEREH TIEEWKELIY KEVMDLEERT KNGVIRGQPS PLGAAVINGS QHPSSSSSVN DVSSMSTDPT LASDTDSSLE AAAGPLGCCR |
| Expression System: | E. coli |
| Concentrations: | 0.5mg/ml (determined by Absorbance at 280nm) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ] |
| Gene ID NCBI: | 5599 |
| Synonyms: | MAPK8; mitogen-activated protein kinase 8; PRKM8; JNK; JNK1; JUN N terminal kinase; SAPK1; MAP kinase 8; JUN N-terminal kinase; c-Jun N-terminal kinase 1; stress-activated protein kinase 1; stress-activated protein kinase 1c; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8 isoform JNK1 alpha1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2; |
| mRNA Refseq: | NM_002750 |
| Protein Refseq: | NP_002741 |
| MIM: | 601158 |
| UniProt ID: | P45983 |
| Chromosome Location: | 10q11 |
| Function: | ATP binding; JUN kinase activity; MAP kinase activity; histone deacetylase binding; histone deacetylase regulator activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity; |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0025 | Human MAGI1 Knockout Cell Line | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0058 | Recombinant Human MAPK8 293 Cell Lysate | Inquiry |
| EL-0059 | Recombinant Human MAPK8 293 Cell Lysate | Inquiry |
| EL-0074 | Recombinant Human MAGEA2 293 Cell Lysate | Inquiry |
| EL-0096 | Recombinant Human MACROD2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| MACROD2 | MAF | MAFF | MAGEA2 |
| MAGI1 | MAGOH | MAK16 | MALT1 |
| MAPK8 | MASH1 | MASP1 | Mat2A |
| MATR3 | MAX | MAZ | |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
