| Cat.No.: | PE-0540 |
| Product Name: | Recombinant Human SMARCC2 |
| Product Overview: | Recombinant full length Human SMRC2 isoform 2 with a N terminal proprietary tag; Predicted MWt 150.30 kDa. |
| Description: | The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Tissue Specificity: | Ubiquitously expressed. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 150.300kDa inclusive of tags |
| Species: | Human |
| Amino Acid Sequence: | MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQ AEPPTNKSLSSLVVQLLQFQEEVFGKHVSNAPLTKLPIKC FLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDII KRHQGTVTEDKNNASHVVYPVPGNLEEEEWVRPVMKRDKQ VLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDE VNSPDSDRRDKKGGNYKKRKRSPSPSPTPEAKKKNAKKGP STPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENST GNKGEQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHA IERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRP TPMGPPPTSHFHVLADTPSGLVPLQPKTPQGRQVDADTKA GRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLL LEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYL EDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKA DPAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEK KEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKV ERDIGEGNLSTAAAAALAAAAVKAKHFAAVEERKIKSLVA LLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGS QPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS PFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSP GTVTPVPPPQ |
| Sequence Similarities: | Belongs to the SMARCC family.Contains 1 SANT domain.Contains 1 SWIRM domain. |
| Expression System: | Wheat germ |
| Protein Length: | 1130 amino acids |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 [ Homo sapiens ] |
| Gene ID NCBI: | 6601 |
| Official Symbol: | SMARCC2 |
| Synonyms: | SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; SWI/SNF complex subunit SMARCC2; BAF170; CRACC2; Rsc8; |
| mRNA Refseq: | NM_139067 |
| Protein Refseq: | NP_620706 |
| MIM: | 601734 |
| UniProt ID: | Q8TAQ2 |
| Chromosome Location: | 12q13.2 |
| Function: | DNA binding; protein binding; transcription coactivator activity; |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0019 | SMARCA4 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0063 | Recombinant Human SMARCC2 293 Cell Lysate | Inquiry |
| EL-0064 | Recombinant Human SMARCB1 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0080 | AZ-505 ditrifluoroacetate | Inquiry |
| ◆ Research Kits | ||
| EKIT-0120 | BRG1 bromodomain TR-FRET Assay Kit | Inquiry |
| Related Gene / Proteins | |||
| SMAD3 | SMAD4 | SMARCA1 | SMARCA2 |
| SMARCA4 | SMARCA5 | SMARCA6 | SMARCAD1 |
| SMARCAL1 | SMARCB1 | SMARCC1 | SMARCC2 |
| SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 |
| SMC1-α | SMC3 | SMC4 | SMCHD1 More > |
| SMCX | SMN | SMN1 | SMN2 |
| SMOC2 | SMRT | SMT3 | SMUG1 |
| SMURF2 | SMYD1 | SMYD2 | SMYD2B |
| SMYD3 | SMYD4 | SMYD5 | |
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