| Cat.No.: | PE-0794 |
| Product Name: | Recombinant Human Protein Kinase C, Beta |
| Product Overview: | Recombinant Human PRKCB is produced in Baculoviral insect expression system. |
| Description: | PKCβI is a member of the PKC family (phospholipid-dependent serine/threonine kinase) and is highly related to PKCβ II. Unlike the mature PKCβ II mRNA and protein, which rapidly increase following acute insulin treatment, the PKCβI mRNA and protein levels remain unchanged. The stable overexpression of PKCbetaII, but not PKCβI, leads to insulin-stimulated glucose uptake into cells. Upon stimulation of B lymphocytes and mast cells, Syk regulates Btk, and Btk selectively regulates enzymatic activity of PKCβI. Specific regulation of PKCβI by Btk is consistent with the selective association of Btk with PKCβI. |
| Applications: | Suitable for use as a standard in Western blot using enhanced chemiluminescence. Use 2-5ul directly from vial (no dilution necessary). For blots using less sensitive substrates, such as alkaline phosphatase, larger amount of protein should be loaded onto the gel. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Purified, Liquid. |
| Species: | Human |
| Expression System: | Baculovirus-Insect Cells |
| Concentrations: | 20ug/ml. |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | PRKCB protein kinase C, beta [ Homo sapiens ] |
| Gene ID NCBI: | 5579 |
| Synonyms: | PRKCB; protein kinase C, beta; PKCB; PRKCB1; PRKCB2; MGC41878; PKC-beta; Protein kinase C beta type; EC 2.7.11.13; PKC-B; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide |
| mRNA Refseq: | NM_002738 |
| Protein Refseq: | NP_002729 |
| MIM: | 176970 |
| UniProt ID: | P05771 |
| Chromosome Location: | 16p11.2 |
| Function: | ATP binding; calcium ion binding; nucleotide binding; protein binding; protein kinase C activity; transferase activity; zinc ion binding |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| BSM-0047 | SGC707 | Inquiry |
| ◆ Antibodies | ||
| EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
| EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
| EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| Pr-SET7 | PRC1 | PRC2 | PRDM1 |
| PRDM10 | PRDM11 | PRDM12 | PRDM13 |
| PRDM14 | PRDM15 | PRDM16 | PRDM17 |
| PRDM2 | PRDM3 | PRDM4 | PRDM5 |
| PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
| PREP1 | PRIM2 | PRKAA2 | PRKCA |
| PRKCB | PRKCE | PRKDC | PRKRIP1 |
| PRMT | prmt1 | PRMT2 | PRMT3 |
| PRMT5 | prmt6 | PRMT7 | PRMT8 |
| PRMT9 | Progerin | Protamine 2 | Prox1 |
| PRPF31 | PRPF40A | PRSS12 | PRSS55 |
| PRTFDC1 | |||
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