| Cat.No.: | PE-1036 |
| Product Name: | Recombinant Human Protein Arginine Methyltransferase 6 |
| Product Overview: | Recombinant Human PRMT6, amino-acids 2-375(end), with N-terminal His-tag, MW=43 kDa, expressed in E. coli. |
| Description: | Protein arginine N-methyltransferase 6 is an enzyme that in humans is encoded by the PRMT6 gene. Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | >45%. |
| Species: | Human |
| Formulation: | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, 20% glycerol, and 3 mM DTT. |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | PRMT6 protein arginine methyltransferase 6 [ Homo sapiens ] |
| Gene ID NCBI: | 55170 |
| Synonyms: | PRMT6; protein arginine methyltransferase 6; HRMT1L6; FLJ10559; FLJ51477;EC 2.1.1.125; protein arginine N-methyltransferase 6; Histone-arginine methyltransferase PRMT6; Protein arginine N-methyltransferase 6; HMT1 hnRNP methyltransferase-like 6 (S. cerevisiae); Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6 |
| mRNA Refseq: | NM_018137 |
| Protein Refseq: | NP_060607 |
| MIM: | 608274 |
| UniProt ID: | Q96LA8 |
| Chromosome Location: | 1p13.2 |
| Function: | histone binding; transferase activity; protein methyltransferase activity; histone methyltransferase activity (H2A-R3 specific); histone methyltransferase activity (H3-R2 specific); histone methyltransferase activity (H4-R3 specific); protein methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| BSM-0047 | SGC707 | Inquiry |
| ◆ Antibodies | ||
| EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
| EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
| EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| Pr-SET7 | PRC1 | PRC2 | PRDM1 |
| PRDM10 | PRDM11 | PRDM12 | PRDM13 |
| PRDM14 | PRDM15 | PRDM16 | PRDM17 |
| PRDM2 | PRDM3 | PRDM4 | PRDM5 |
| PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
| PREP1 | PRIM2 | PRKAA2 | PRKCA |
| PRKCB | PRKCE | PRKDC | PRKRIP1 |
| PRMT | prmt1 | PRMT2 | PRMT3 |
| PRMT5 | prmt6 | PRMT7 | PRMT8 |
| PRMT9 | Progerin | Protamine 2 | Prox1 |
| PRPF31 | PRPF40A | PRSS12 | PRSS55 |
| PRTFDC1 | |||
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