| Cat.No.: | PE-1125 |
| Product Name: | Recombinant Human NCOA1, His-tagged |
| Product Overview: | Recombinant fragment, corresponding to amino acids 627-786 of Human KAT13A / SRC1, with a His tag, Predicted MWt 18 kDa. |
| Description: | The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Tissue Specificity: | Widely expressed. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Purity: | >95% by SDS-PAGE |
| Species: | Human |
| Tag: | His |
| Sequence Similarities: | Belongs to the SRC/p160 nuclear receptor coactivator family.Contains 1 basic helix-loop-helix (bHLH) domain.Contains 1 PAS (PER-ARNT-SIM) domain. |
| Activity: | 1 unit equals 1 nanogram of purified protein. |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | NCOA1 nuclear receptor coactivator 1 [ Homo sapiens ] |
| Gene ID NCBI: | 8648 |
| Official Symbol: | NCOA1 |
| Synonyms: | NCOA1; nuclear receptor coactivator 1; bHLHe74; F SRC 1; KAT13A; NCoA 1; RIP160; SRC1; |
| mRNA Refseq: | NM_003743 |
| Protein Refseq: | NP_003734 |
| MIM: | 602691 |
| UniProt ID: | Q15788 |
| Chromosome Location: | 2p23 |
| Product Types | ||
| ◆ Research Kits | ||
| EKIT-0046 | HDAC3/NCOR1 fluorometric drug discovery Kit | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0046 | Recombinant Human NCOR1, GST-tagged | Inquiry |
| ◆ Antibodies | ||
| EAb-0065 | NCOA1 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0143 | Recombinant Human NCOA1 293 Cell Lysate | Inquiry |
| EL-0144 | Recombinant Human NCOA2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| NCAPD3 | NCAPH2 | NCOA1 | NCOA2 |
| NCOA3 | NCoA4 | NCOR1 | ncor2 |
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