Cat.No.: | PE-1126 |
Product Name: | Recombinant Human NCOA1, His-tagged |
Product Overview: | Recombinant fragment, corresponding to amino acids 627-786 of Human KAT13A / SRC1 with a His tag and Tobacco Etch virus protease site, Predicted MWt 19 kDa. |
Description: | The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Tissue Specificity: | Widely expressed. |
Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
Appearance: | Liquid |
Purity: | >95% by SDS-PAGE |
Species: | Human |
Tag: | His |
Sequence Similarities: | Belongs to the SRC/p160 nuclear receptor coactivator family.Contains 1 basic helix-loop-helix (bHLH) domain.Contains 1 PAS (PER-ARNT-SIM) domain. |
Expression System: | E. coli |
Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name: | NCOA1 nuclear receptor coactivator 1 [ Homo sapiens ] |
Gene ID NCBI: | 8648 |
Official Symbol: | NCOA1 |
Synonyms: | NCOA1; nuclear receptor coactivator 1; bHLHe74; F SRC 1; KAT13A; NCoA 1; RIP160; SRC1; |
mRNA Refseq: | NM_003743 |
Protein Refseq: | NP_003734 |
MIM: | 602691 |
UniProt ID: | Q15788 |
Chromosome Location: | 2p23 |
Product Types | ||
◆ Research Kits | ||
EKIT-0046 | HDAC3/NCOR1 fluorometric drug discovery Kit | Inquiry |
◆ Proteins & Enzymes | ||
PE-0046 | Recombinant Human NCOR1, GST-tagged | Inquiry |
◆ Antibodies | ||
EAb-0065 | NCOA1 Polyclonal Antibody | Inquiry |
◆ Extracts & Lysates | ||
EL-0143 | Recombinant Human NCOA1 293 Cell Lysate | Inquiry |
EL-0144 | Recombinant Human NCOA2 293 Cell Lysate | Inquiry |
Related Gene / Proteins | |||
NCAPD3 | NCAPH2 | NCOA1 | NCOA2 |
NCOA3 | NCoA4 | NCOR1 | ncor2 |
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